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Peptide record

TPDB38805

Neurotoxin Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB38805
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
VKRCCDEEECSSACWPCCWG
Physicochemical Analysis
C92H136N26O31S6
NQHILMFTY
C
2294.61
4.16
2
4
4
-2
4.57
-0.340
19.50
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
11375
495.73
8
Residue Composition
number
1
A
1
R
0
N
1
D
6
C
3
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
2
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 6 E: 3 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 2 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
20
C92H136N26O31S6
2294.61
4.16
-2
4.57
-0.340
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus pennaceus (Feathered cone) (Conus episcopus)
Neurotoxin
Conotoxin PnMLKM-D0211
cone snail
Conotoxin M superfamily
Evidence at transcript level
Amidation Cleavage on pair of basic residues Disulfide bond Hydroxylation Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:11158371}.
Additional Detail Fields 7 fields
Amidation Cleavage on pair of basic residues Disulfide bond Hydroxylation Neurotoxin Secreted Toxin
Neurotoxin
Evidence at transcript level
Conotoxin M superfamily
Conotoxin PnMLKM-D0211
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:11158371}.
cone snail