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Peptide record

TPDB38736

Neurotoxin Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB38736
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
VGCEEDPMHCKGKQAKPTCCNGVCNCNV
Physicochemical Analysis
C116H191N37O40S7
RILFSWY
C
2968.44
6.75
4
3
5
-0
10.48
-0.471
34.64
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
375
12.63
11
Residue Composition
number
1
A
0
R
3
N
1
D
6
C
2
E
1
Q
3
G
1
H
0
I
0
L
3
K
1
M
0
F
2
P
0
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 3 D: 1 C: 6 E: 2 Q: 1 G: 3 H: 1 I: 0 L: 0 K: 3 M: 1 F: 0 P: 2 S: 0 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
28
C116H191N37O40S7
2968.44
6.75
-0
10.48
-0.471
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Blocks potassium channels. {ECO:0000250}.

Target

voltage-gated potassium channel (Kv)

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Hottentotta tamulus sindicus (Scorpion) (Buthus sindicus)
Neurotoxin Ion channel impairing toxin Potassium channel impairing toxin
Blocks potassium channels..
Peptide 2 (Peptide II)
scorpion
Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 09 subfamily
Evidence at protein level
Direct protein sequencing Ion channel impairing toxin Neurotoxin Potassium channel impairing toxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:2583272}.
Additional Detail Fields 7 fields
Direct protein sequencing Ion channel impairing toxin Neurotoxin Potassium channel impairing toxin Secreted Toxin
Neurotoxin Ion channel impairing toxin Potassium channel impairing toxin
Evidence at protein level
Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 09 subfamily
Peptide 2 (Peptide II)
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:2583272}.
scorpion