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Peptide record

TPDB38734

Neurotoxin Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB38734
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
VGCEECPMHCKGKNAVPTCDNGVCNCNA
Physicochemical Analysis
C112H182N36O40S7
RQILFSWY
C
2897.31
5.34
3
3
6
-1
9.16
-0.268
38.21
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
375
12.94
11
Residue Composition
number
2
A
0
R
4
N
1
D
6
C
2
E
0
Q
3
G
1
H
0
I
0
L
2
K
1
M
0
F
2
P
0
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 4 D: 1 C: 6 E: 2 Q: 0 G: 3 H: 1 I: 0 L: 0 K: 2 M: 1 F: 0 P: 2 S: 0 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
28
C112H182N36O40S7
2897.31
5.34
-1
9.16
-0.268
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Blocks Shaker potassium channels. {ECO:0000269|Ref.1}.

Target

voltage-gated potassium channel (Kv)

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)
Neurotoxin Ion channel impairing toxin Potassium channel impairing toxin Voltage-gated potassium channel impairing toxin
Blocks Shaker potassium channels..
Potassium channel toxin alpha-KTx 9.10 (Toxin MeuKTx-5)
scorpion
Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 09 subfamily
Evidence at protein level
Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Potassium channel impairing toxin Secreted Toxin Voltage-gated potassium channel impairing toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|Ref.1}.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Potassium channel impairing toxin Secreted Toxin Voltage-gated potassium channel impairing toxin
Neurotoxin Ion channel impairing toxin Potassium channel impairing toxin Voltage-gated potassium channel impairing toxin
Evidence at protein level
Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 09 subfamily
Potassium channel toxin alpha-KTx 9.10 (Toxin MeuKTx-5)
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|Ref.1}.
scorpion