TPDB

3D PDB MODEL

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TPDB ID TPDB38149

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 121-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

SLVELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTNCDPKKDRYSYDWKNKTIVCGEENPCLKQLCECDKAVAICLRENKGTYNKKRDVYLKPFCDKGRDC

FASTA

>TPDB38149|Toxicity|length=121
SLVELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTNCDPKKDRYSYDWKNKTIVCGEENPCLKQLCECDKAVAICLRENKGTYNKKRDVYLKPFCDKGRDC

Formula C590H950N170O177S15

Absent Amino Acids

Common Amino Acids K

Mass 13737.97

PI 8.64

Basic Residues 26

Acidic Residues 15

Hydrophobic Residues 34

Net Charge +9

Boman Index 34.87

Hydrophobicity -0.793

Aliphatic Index 57.19

Half Life

Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 18295

Absorbance 280nm 133.17

Polar Residues 39

number

5

A

6

R

7

N

9

D

14

C

6

E

2

Q

10

G

1

H

3

I

9

L

19

K

1

M

1

F

5

P

3

S

5

T

1

W

8

Y

6

V

Amino Acid Distribution

A: 5 R: 6 N: 7 D: 9 C: 14 E: 6 Q: 2 G: 10 H: 1 I: 3 L: 9 K: 19 M: 1 F: 1 P: 5 S: 3 T: 5 W: 1 Y: 8 V: 6

Length

121

Formula

C590H950N170O177S15

Mass

13737.97

PI

8.64

Net Charge

+9

Boman Index

34.87

Hydrophobicity

-0.793

Evidence 1 Activity

Source & Reference

Database Source NA