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Peptide record

TPDB38118

Antiviral Toxicity standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB38118
Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AVPpred-BWR dbAMP 3.0 DRAMP DRAVP 2.0 Peptipedia
standard
No
A 42-aa standard natural multi-activity (Antiviral and Toxicity) peptide sequence curated from AVPpred-BWR, dbAMP 3.0, DRAMP, and other sources, with an available 3D structural model.
Sequence
SLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKELGSGSGC
Physicochemical Analysis
C211H341N49O72S2
RHPW
EL
4780.43
4.14
5
10
16
-5
16.04
-0.379
102.14
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
2980
62.34
10
Residue Composition
number
1
A
0
R
1
N
3
D
1
C
7
E
1
Q
3
G
0
H
3
I
7
L
5
K
1
M
1
F
0
P
4
S
1
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 3 C: 1 E: 7 Q: 1 G: 3 H: 0 I: 3 L: 7 K: 5 M: 1 F: 1 P: 0 S: 4 T: 1 W: 0 Y: 2 V: 1
Chemical Descriptors
42
C211H341N49O72S2
4780.43
4.14
-5
16.04
-0.379
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.33082259]Human embryonic kidney HEK293T cells:<5% Cytotoxicity at 10 µM Vero E6 cells:18% Cytotoxicity at 10 µM.

Source & Reference

NA
DRAMP
mBio. 2020 Oct 20 11(5):e01935-20.