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Peptide record

TPDB37911

Neurotoxin Toxicity standard
47 amino acids
Basic Information
3D PDB MODEL
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TPDB37911
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 47-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
SCFEGGKDCKNDCQCCGKWSYCKCPIWGLFGCSCVIGDSMVEVRKCQ
Physicochemical Analysis
C218H336N60O66S11
AHT
C
5206.09
7.37
6
5
12
+1
5.60
-0.094
43.40
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
13115
251.92
18
Residue Composition
number
0
A
1
R
1
N
3
D
10
C
2
E
2
Q
6
G
0
H
2
I
1
L
5
K
1
M
2
F
1
P
4
S
0
T
2
W
1
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 3 C: 10 E: 2 Q: 2 G: 6 H: 0 I: 2 L: 1 K: 5 M: 1 F: 2 P: 1 S: 4 T: 0 W: 2 Y: 1 V: 3
Chemical Descriptors
47
C218H336N60O66S11
5206.09
7.37
+1
5.60
-0.094
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Neurotoxin. Causes spastic paralysis and death in mice by intracerebroventricular injection at dose levels of 3 ug per mouse. {ECO:0000269|Ref.1}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Phoneutria nigriventer (Brazilian armed spider) (Ctenus nigriventer)
Neurotoxin
Neurotoxin. Causes spastic paralysis and death in mice by intracerebroventricular injection at dose levels of 3 ug per mouse..
U18-ctenitoxin-Pn1a (U18-CNTX-Pn1a) (Neurotoxin PNTx30C3)
spider
Neurotoxin 37 family
Evidence at protein level
Direct protein sequencing Disulfide bond Knottin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000269|Ref.1}.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Knottin Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Neurotoxin 37 family
U18-ctenitoxin-Pn1a (U18-CNTX-Pn1a) (Neurotoxin PNTx30C3)
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000269|Ref.1}.
spider