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Peptide record

TPDB37828

Neurotoxin Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB37828
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
RWDVDQCIYYCLNGVVGYSYTECQTMCT
Physicochemical Analysis
C143H209N35O46S5
AHKFP
CY
3314.74
3.70
1
3
11
-2
-0.02
-0.089
58.93
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11710
353.27
15
Residue Composition
number
0
A
1
R
1
N
2
D
4
C
1
E
2
Q
2
G
0
H
1
I
1
L
0
K
1
M
0
F
0
P
1
S
3
T
1
W
4
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 2 C: 4 E: 1 Q: 2 G: 2 H: 0 I: 1 L: 1 K: 0 M: 1 F: 0 P: 0 S: 1 T: 3 W: 1 Y: 4 V: 3
Chemical Descriptors
28
C143H209N35O46S5
3314.74
3.70
-2
-0.02
-0.089
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: In vivo, intracranial injection elicits scratching and grooming activity in mice, and causes body and rear limb extension and tail curling immediately upon injection. {ECO:0000269|PubMed:18206266}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus cancellatus (Cancellate cone) (Conus austini)
Neurotoxin
In vivo, intracranial injection elicits scratching and grooming activity in mice, and causes body and rear limb extension and tail curling immediately upon injection..
Conotoxin as14b (Conotoxin AsXIVB)
cone snail
Conotoxin L superfamily
Evidence at protein level
Direct protein sequencing Disulfide bond Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305}.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Conotoxin L superfamily
Conotoxin as14b (Conotoxin AsXIVB)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305}.
cone snail