Peptide record

TPDB37774

Neurotoxin Toxicity standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB37774
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 39-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
RRSLTRRVPEECEESCEEEEKTCCGLENGQPFCSRICWG
Physicochemical Analysis
C184H294N58O65S6
ADHMY
E
4551.07
4.55
6
9
6
-3
20.04
-1.023
37.44
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5875
129.09
13
Residue Composition
number
0
A
5
R
1
N
0
D
6
C
9
E
1
Q
3
G
0
H
1
I
2
L
1
K
0
M
1
F
2
P
3
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 0 C: 6 E: 9 Q: 1 G: 3 H: 0 I: 1 L: 2 K: 1 M: 0 F: 1 P: 2 S: 3 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
39
C184H294N58O65S6
4551.07
4.55
-3
20.04
-1.023
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus arenatus (Sand-dusted cone)
Neurotoxin
Conotoxin ArMSGL-013
cone snail
Conotoxin O3 superfamily
Evidence at transcript level
Amidation Cleavage on pair of basic residues Disulfide bond Knottin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305}.
Additional Detail Fields 7 fields
Amidation Cleavage on pair of basic residues Disulfide bond Knottin Neurotoxin Secreted Toxin
Neurotoxin
Evidence at transcript level
Conotoxin O3 superfamily
Conotoxin ArMSGL-013
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305}.
cone snail