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Peptide record

TPDB37647

Toxicity standard
59 amino acids
Basic Information
3D PDB MODEL
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TPDB37647
Toxicity
Toxicity and safety peptides
Peptipedia
standard
No
A 59-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RICYSHKLLQAKTTKTCEENSCYKRSLPKIPLIIIGRGCGCPLTLPFLRIKCCTSDKCN
Physicochemical Analysis
C289H487N83O80S8
MWV
C
6661.03
9.24
12
3
17
+8
9.99
-0.139
87.63
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
3480
52.24
22
Residue Composition
number
1
A
4
R
2
N
1
D
8
C
2
E
1
Q
3
G
1
H
6
I
7
L
7
K
0
M
1
F
4
P
4
S
5
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 2 D: 1 C: 8 E: 2 Q: 1 G: 3 H: 1 I: 6 L: 7 K: 7 M: 0 F: 1 P: 4 S: 4 T: 5 W: 0 Y: 2 V: 0
Chemical Descriptors
59
C289H487N83O80S8
6661.03
9.24
+8
9.99
-0.139
Evidence Records 1 records
Evidence 1 Activity

Activity

LC50
Toxicity
600 µg/mL
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: LC50>600 µg/mL | Cytotoxicity: HUVEC: LC50=57±3 µg/mL

Target

erythrocytes

Source & Reference

NA
DRAMP
J Venom Res. 2014 Jun 19 5:16-21.