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Peptide record

TPDB37410

Neurotoxin Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB37410
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 11-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
RCCGYKMCHPC
Physicochemical Analysis
C51H81N17O13S5
ANDEQILFSTWV
C
1300.61
8.30
3
0
2
+2
1.09
-0.273
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1740
133.78
5
Residue Composition
number
0
A
1
R
0
N
0
D
4
C
0
E
0
Q
1
G
1
H
0
I
0
L
1
K
1
M
0
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 1 M: 1 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
11
C51H81N17O13S5
1300.61
8.30
+2
1.09
-0.273
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Chi-conotoxins inhibit the neuronal noradrenaline transporter (NET/SLC6A2). {ECO:0000250|UniProtKB:P58808}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus araneosus (Cobweb cone)
Neurotoxin
Chi-conotoxins inhibit the neuronal noradrenaline transporter (NET/SLC6A2)..
Chi-conotoxin-like Ar1311
cone snail
Conotoxin T superfamily
Evidence at protein level
Direct protein sequencing Disulfide bond Hydroxylation Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:20843009}.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Hydroxylation Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Conotoxin T superfamily
Chi-conotoxin-like Ar1311
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:20843009}.
cone snail