TPDB

3D PDB MODEL

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TPDB ID TPDB36447

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 146-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

PTSVAVDQGSMVSNSPGEWCWPGMGYPVYPFPRCRALVKSQCAGGQVVESIQKDCCRQIAAIGDEWCICGALGSMRGSMYKELGVALADDKATVAEVFPGCRTEVMDRAVASLPAVCNQYIPNTNGTDGVCYWLSYYQPPRQMSSR

FASTA

>TPDB36447|Toxicity|length=146
PTSVAVDQGSMVSNSPGEWCWPGMGYPVYPFPRCRALVKSQCAGGQVVESIQKDCCRQIAAIGDEWCICGALGSMRGSMYKELGVALADDKATVAEVFPGCRTEVMDRAVASLPAVCNQYIPNTNGTDGVCYWLSYYQPPRQMSSR

Formula C685H1062N190O209S16

Absent Amino Acids H

Common Amino Acids GV

Mass 15816.08

PI 5.15

Basic Residues 12

Acidic Residues 13

Hydrophobic Residues 57

Net Charge -1

Boman Index 18.68

Hydrophobicity -0.127

Aliphatic Index 66.10

Half Life

Mammalian: >20 hour Yeast: >20 hour E.coli: ?

Extinction Coefficient Cystines 33055

Absorbance 280nm 209.00

Polar Residues 46

number

13

A

8

R

4

N

7

D

10

C

6

E

8

Q

14

G

0

H

5

I

6

L

4

K

6

M

2

F

11

P

12

S

5

T

4

W

7

Y

14

V

Amino Acid Distribution

A: 13 R: 8 N: 4 D: 7 C: 10 E: 6 Q: 8 G: 14 H: 0 I: 5 L: 6 K: 4 M: 6 F: 2 P: 11 S: 12 T: 5 W: 4 Y: 7 V: 14

Length

146

Formula

C685H1062N190O209S16

Mass

15816.08

PI

5.15

Net Charge

-1

Boman Index

18.68

Hydrophobicity

-0.127

Evidence 1 Activity

Source & Reference

Database Source NA