TPDB

3D PDB MODEL

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TPDB ID TPDB35906

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 118-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

NLIQFKNMIQCAGTRPWTAYVNYGCYCGKGGSGTPVDELDRCCYTHDNCYNEAEKIPGCNPNIKTYSYTCTEPNLTCTDTADTCARFLCDCDRTAAICFASAPYNSNNVMISSSTNCQ

FASTA

>TPDB35906|Toxicity|length=118
NLIQFKNMIQCAGTRPWTAYVNYGCYCGKGGSGTPVDELDRCCYTHDNCYNEAEKIPGCNPNIKTYSYTCTEPNLTCTDTADTCARFLCDCDRTAAICFASAPYNSNNVMISSSTNCQ

Formula C546H832N152O184S16

Absent Amino Acids

Common Amino Acids C

Mass 12982.48

PI 4.67

Basic Residues 9

Acidic Residues 11

Hydrophobic Residues 36

Net Charge -4

Boman Index 15.13

Hydrophobicity -0.407

Aliphatic Index 48.05

Half Life

Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour

Extinction Coefficient Cystines 18295

Absorbance 280nm 140.92

Polar Residues 57

number

9

A

4

R

12

N

7

D

14

C

4

E

3

Q

7

G

1

H

6

I

4

L

4

K

2

M

3

F

6

P

7

S

13

T

1

W

8

Y

3

V

Amino Acid Distribution

A: 9 R: 4 N: 12 D: 7 C: 14 E: 4 Q: 3 G: 7 H: 1 I: 6 L: 4 K: 4 M: 2 F: 3 P: 6 S: 7 T: 13 W: 1 Y: 8 V: 3

Length

118

Formula

C546H832N152O184S16

Mass

12982.48

PI

4.67

Net Charge

-4

Boman Index

15.13

Hydrophobicity

-0.407

Evidence 1 Activity

Source & Reference

Database Source NA