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Peptide record

TPDB35898

Neurotoxin Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB35898
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
NIQIICCKHTPACCT
Physicochemical Analysis
C67H114N20O20S4
RDEGLMFSWYV
C
1648.00
7.85
2
0
4
+1
1.62
0.547
84.67
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
250
15.17
8
Residue Composition
number
1
A
0
R
1
N
0
D
4
C
0
E
1
Q
0
G
1
H
3
I
0
L
1
K
0
M
0
F
1
P
0
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 4 E: 0 Q: 1 G: 0 H: 1 I: 3 L: 0 K: 1 M: 0 F: 0 P: 1 S: 0 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C67H114N20O20S4
1648.00
7.85
+1
1.62
0.547
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus textile (Cloth-of-gold cone)
Neurotoxin
Conotoxin tx5d (Trixin)
cone snail
Conotoxin T superfamily
Evidence at protein level
Amidation Direct protein sequencing Disulfide bond Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct (PubMed:19380747, PubMed:23031820). Is mostly present in part 5 of the venom duct (distal part near the pharynx), and less abundantly present in part 4 of the venom duct (PubMed:23031820). {ECO:0000305|PubMed:19380747, ECO:0000305|PubMed:23031820}.
Additional Detail Fields 7 fields
Amidation Direct protein sequencing Disulfide bond Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Conotoxin T superfamily
Conotoxin tx5d (Trixin)
TISSUE SPECIFICITY: Expressed by the venom duct (PubMed:19380747, PubMed:23031820). Is mostly present in part 5 of the venom duct (distal part near the pharynx), and less abundantly present in part 4 of the venom duct (PubMed:23031820). {ECO:0000305|PubMed:19380747, ECO:0000305|PubMed:23031820}.
cone snail