TPDB

3D PDB MODEL

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TPDB ID TPDB35740

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 144-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MVKAVTVLNSSEGVTGTVYFTQEGDGLTTVTGNLSGLKPGLHGFHVHALGDTTNGCMSTGPHFNPVGKEHGAPGDENRHAGDLGTAAINIVDKQIPLTGPHSIIGRAVVVHSDPDDLGRGCHELSKSTGNAGGRVACGIIGLQG

FASTA

>TPDB35740|Toxicity|length=144
MVKAVTVLNSSEGVTGTVYFTQEGDGLTTVTGNLSGLKPGLHGFHVHALGDTTNGCMSTGPHFNPVGKEHGAPGDENRHAGDLGTAAINIVDKQIPLTGPHSIIGRAVVVHSDPDDLGRGCHELSKSTGNAGGRVACGIIGLQG

Formula C626H1001N189O203S5

Absent Amino Acids W

Common Amino Acids G

Mass 14583.28

PI 6.12

Basic Residues 18

Acidic Residues 13

Hydrophobic Residues 46

Net Charge -3

Boman Index 33.26

Hydrophobicity -0.149

Aliphatic Index 81.18

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1615

Absorbance 280nm 11.07

Polar Residues 35

number

9

A

4

R

7

N

8

D

3

C

5

E

3

Q

26

G

9

H

7

I

11

L

5

K

2

M

3

F

7

P

8

S

13

T

0

W

1

Y

13

V

Amino Acid Distribution

A: 9 R: 4 N: 7 D: 8 C: 3 E: 5 Q: 3 G: 26 H: 9 I: 7 L: 11 K: 5 M: 2 F: 3 P: 7 S: 8 T: 13 W: 0 Y: 1 V: 13

Length

144

Formula

C626H1001N189O203S5

Mass

14583.28

PI

6.12

Net Charge

-3

Boman Index

33.26

Hydrophobicity

-0.149

Evidence 1 Activity

Source & Reference

Database Source NA