TPDB

3D PDB MODEL

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TPDB ID TPDB35582

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 131-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MSWQAYVDEHLMCEIEGHHLASAAILGHDGTVWAQSADFPQFKPEEITGIMKDFDEPGHLAPTGMFVAAAKYMVIQGEPGAVIRGKKGAGGITIKKTGQALVVGIYDEPMTPGQCNMVVERLGDYLLKQGL

FASTA

>TPDB35582|Toxicity|length=131
MSWQAYVDEHLMCEIEGHHLASAAILGHDGTVWAQSADFPQFKPEEITGIMKDFDEPGHLAPTGMFVAAAKYMVIQGEPGAVIRGKKGAGGITIKKTGQALVVGIYDEPMTPGQCNMVVERLGDYLLKQGL

Formula C631H983N165O185S9

Absent Amino Acids

Common Amino Acids G

Mass 14129.28

PI 5.09

Basic Residues 15

Acidic Residues 16

Hydrophobic Residues 57

Net Charge -6

Boman Index 26.68

Hydrophobicity -0.049

Aliphatic Index 83.44

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 17085

Absorbance 280nm 120.92

Polar Residues 23

number

13

A

2

R

1

N

7

D

2

C

9

E

7

Q

17

G

5

H

9

I

9

L

8

K

7

M

4

F

7

P

3

S

6

T

2

W

4

Y

9

V

Amino Acid Distribution

A: 13 R: 2 N: 1 D: 7 C: 2 E: 9 Q: 7 G: 17 H: 5 I: 9 L: 9 K: 8 M: 7 F: 4 P: 7 S: 3 T: 6 W: 2 Y: 4 V: 9

Length

131

Formula

C631H983N165O185S9

Mass

14129.28

PI

5.09

Net Charge

-6

Boman Index

26.68

Hydrophobicity

-0.049

Evidence 1 Activity

Source & Reference

Database Source NA