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Peptide record

TPDB35494

Neurotoxin Toxicity standard
91 amino acids
Basic Information
3D PDB MODEL
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TPDB35494
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 91-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
MSKVGVVPLIFLVLLSIAALQNGDDPRRQRDEKQSPQGDILRSTLTKYSYNIQRRCWAGGSPCHLCSSSQVCIAPTGHPAIMCGRCVPILT
Physicochemical Analysis
C430H706N128O125S8
LS
9925.60
8.88
12
5
33
+5
12.37
-0.012
93.19
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
8855
89.21
29
Residue Composition
number
5
A
7
R
2
N
4
D
6
C
1
E
6
Q
7
G
2
H
7
I
9
L
3
K
2
M
1
F
7
P
9
S
4
T
1
W
2
Y
6
V
Amino Acid Distribution
A: 5 R: 7 N: 2 D: 4 C: 6 E: 1 Q: 6 G: 7 H: 2 I: 7 L: 9 K: 3 M: 2 F: 1 P: 7 S: 9 T: 4 W: 1 Y: 2 V: 6
Chemical Descriptors
91
C430H706N128O125S8
9925.60
8.88
+5
12.37
-0.012
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin. {ECO:0000305}.

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus imperialis (Imperial cone)
Neurotoxin
Probable neurotoxin..
Conotoxin Im9.1 (Conopeptide im015)
cone snail
Conotoxin M superfamily
Evidence at protein level
Cleavage on pair of basic residues Disulfide bond Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
Additional Detail Fields 7 fields
Cleavage on pair of basic residues Disulfide bond Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at protein level
Conotoxin M superfamily
Conotoxin Im9.1 (Conopeptide im015)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
cone snail