Back to search

Peptide record

TPDB35438

Neurotoxin Toxicity standard
80 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB35438
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 80-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
MSGLGIMVLTLLLLVSMATSHQDGGGKQATQRDAINVRRRRSITRREVVTEECEEYCKEQNKTCCGLTNGRPRCVGVCFG
Physicochemical Analysis
C366H621N119O116S9
W
RG
8833.22
8.59
13
8
25
+4
22.35
-0.301
77.88
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
21.11
25
Residue Composition
number
3
A
9
R
3
N
2
D
6
C
6
E
4
Q
9
G
1
H
3
I
7
L
3
K
3
M
1
F
1
P
4
S
7
T
0
W
1
Y
7
V
Amino Acid Distribution
A: 3 R: 9 N: 3 D: 2 C: 6 E: 6 Q: 4 G: 9 H: 1 I: 3 L: 7 K: 3 M: 3 F: 1 P: 1 S: 4 T: 7 W: 0 Y: 1 V: 7
Chemical Descriptors
80
C366H621N119O116S9
8833.22
8.59
+4
22.35
-0.301
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus ventricosus (Mediterranean cone)
Neurotoxin
Conotoxin VnMSGL-0123
cone snail
Conotoxin O3 superfamily
Evidence at transcript level
Amidation Cleavage on pair of basic residues Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct.
Additional Detail Fields 7 fields
Amidation Cleavage on pair of basic residues Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at transcript level
Conotoxin O3 superfamily
Conotoxin VnMSGL-0123
TISSUE SPECIFICITY: Expressed by the venom duct.
cone snail