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Peptide record

TPDB35334

Neurotoxin Toxicity standard
94 amino acids
Basic Information
3D PDB MODEL
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TPDB35334
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 94-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
MRLTTMHSVILMLLLVFAFDNVDGDEPGQTARDVDNRNFMSILRSEGKPVHFLRAIKKRDCTGQACTTGDNCPSECVCNEHHFCTGKCCYFLHA
Physicochemical Analysis
C453H713N133O136S12
W
CL
10583.17
6.55
15
11
33
-1
20.08
-0.167
69.47
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1990
18.80
27
Residue Composition
number
5
A
6
R
5
N
7
D
8
C
4
E
2
Q
6
G
5
H
3
I
8
L
4
K
4
M
6
F
3
P
4
S
7
T
0
W
1
Y
6
V
Amino Acid Distribution
A: 5 R: 6 N: 5 D: 7 C: 8 E: 4 Q: 2 G: 6 H: 5 I: 3 L: 8 K: 4 M: 4 F: 6 P: 3 S: 4 T: 7 W: 0 Y: 1 V: 6
Chemical Descriptors
94
C453H713N133O136S12
10583.17
6.55
-1
20.08
-0.167
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin. {ECO:0000305}.

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus imperialis (Imperial cone)
Neurotoxin
Probable neurotoxin..
Conotoxin Im026 (Conopeptide im026)
cone snail
Evidence at protein level
Cleavage on pair of basic residues Disulfide bond Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
Additional Detail Fields 6 fields
Cleavage on pair of basic residues Disulfide bond Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at protein level
Conotoxin Im026 (Conopeptide im026)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
cone snail