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Peptide record

TPDB35289

Neurotoxin Toxicity standard
81 amino acids
Basic Information
3D PDB MODEL
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TPDB35289
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 81-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
MQKLTILLLVAAVLMSTQALNQEQHQRAKINLLSKRKPPAERWWRWGGCMLWFGRCTKDSECCSNSCDRTYCELARFPSDW
Physicochemical Analysis
C417H656N122O115S9
L
9507.08
8.88
13
7
31
+5
8.55
-0.415
72.35
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
29365
308.87
25
Residue Composition
number
6
A
7
R
3
N
3
D
6
C
4
E
5
Q
3
G
1
H
2
I
10
L
5
K
3
M
2
F
3
P
6
S
4
T
5
W
1
Y
2
V
Amino Acid Distribution
A: 6 R: 7 N: 3 D: 3 C: 6 E: 4 Q: 5 G: 3 H: 1 I: 2 L: 10 K: 5 M: 3 F: 2 P: 3 S: 6 T: 4 W: 5 Y: 1 V: 2
Chemical Descriptors
81
C417H656N122O115S9
9507.08
8.88
+5
8.55
-0.415
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Gamma-conotoxins may act on voltage-gated non-specific cation pacemaker channels (HCN). {ECO:0000250}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus textile (Cloth-of-gold cone)
Neurotoxin Ion channel impairing toxin
Gamma-conotoxins may act on voltage-gated non-specific cation pacemaker channels (HCN)..
Gamma-conotoxin-like TeA53
cone snail
Conotoxin O2 superfamily
Evidence at transcript level
Disulfide bond Ion channel impairing toxin Knottin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct.
Additional Detail Fields 7 fields
Disulfide bond Ion channel impairing toxin Knottin Neurotoxin Secreted Signal Toxin
Neurotoxin Ion channel impairing toxin
Evidence at transcript level
Conotoxin O2 superfamily
Gamma-conotoxin-like TeA53
TISSUE SPECIFICITY: Expressed by the venom duct.
cone snail