TPDB

3D PDB MODEL

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TPDB ID TPDB35202

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 106-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MPKLAVVLLVLLILPLSYFDVAGGQAEQGDWRGNRLARDLQRGGRDDESECIINTRDSPWGRCCRTRMCGSMCCPETVAPASIIGEGAMGVPAQDSCSAHSPFFSS

FASTA

>TPDB35202|Toxicity|length=106
MPKLAVVLLVLLILPLSYFDVAGGQAEQGDWRGNRLARDLQRGGRDDESECIINTRDSPWGRCCRTRMCGSMCCPETVAPASIIGEGAMGVPAQDSCSAHSPFFSS

Formula C486H776N144O151S11

Absent Amino Acids

Common Amino Acids G

Mass 11405.04

PI 5.05

Basic Residues 11

Acidic Residues 12

Hydrophobic Residues 39

Net Charge -2

Boman Index 17.76

Hydrophobicity -0.074

Aliphatic Index 76.42

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 12865

Absorbance 280nm 112.80

Polar Residues 27

number

9

A

9

R

2

N

7

D

7

C

5

E

4

Q

11

G

1

H

5

I

9

L

1

K

4

M

3

F

7

P

10

S

3

T

2

W

1

Y

6

V

Amino Acid Distribution

A: 9 R: 9 N: 2 D: 7 C: 7 E: 5 Q: 4 G: 11 H: 1 I: 5 L: 9 K: 1 M: 4 F: 3 P: 7 S: 10 T: 3 W: 2 Y: 1 V: 6

Length

106

Formula

C486H776N144O151S11

Mass

11405.04

PI

5.05

Net Charge

-2

Boman Index

17.76

Hydrophobicity

-0.074

Evidence 1 Activity

Source & Reference

Database Source NA