TPDB

3D PDB MODEL

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TPDB ID TPDB35146

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 130-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MPIEGKYKLEKSDNFDKFLDELGVGFMVKTAAKTLKPTLEVDVQGDTYVFRSLSTFKNTEIKFKLGEEFEEDRADGKRVKTVVNKEGDNKFIQTQYGDKEVKIVRDFQGDDVVVTASVGDVTSVRTYKRI

FASTA

>TPDB35146|Toxicity|length=130
MPIEGKYKLEKSDNFDKFLDELGVGFMVKTAAKTLKPTLEVDVQGDTYVFRSLSTFKNTEIKFKLGEEFEEDRADGKRVKTVVNKEGDNKFIQTQYGDKEVKIVRDFQGDDVVVTASVGDVTSVRTYKRI

Formula C661H1053N173O207S2

Absent Amino Acids CHW

Common Amino Acids K

Mass 14799.79

PI 5.44

Basic Residues 23

Acidic Residues 24

Hydrophobic Residues 47

Net Charge -1

Boman Index 47.67

Hydrophobicity -0.592

Aliphatic Index 74.77

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 5960

Absorbance 280nm 40.27

Polar Residues 28

number

4

A

6

R

4

N

13

D

0

C

11

E

4

Q

10

G

0

H

5

I

7

L

17

K

2

M

9

F

2

P

5

S

11

T

0

W

4

Y

16

V

Amino Acid Distribution

A: 4 R: 6 N: 4 D: 13 C: 0 E: 11 Q: 4 G: 10 H: 0 I: 5 L: 7 K: 17 M: 2 F: 9 P: 2 S: 5 T: 11 W: 0 Y: 4 V: 16

Length

130

Formula

C661H1053N173O207S2

Mass

14799.79

PI

5.44

Net Charge

-1

Boman Index

47.67

Hydrophobicity

-0.592

Evidence 1 Activity

Source & Reference

Database Source NA