Back to search

Peptide record

TPDB34959

Neurotoxin Toxicity standard
90 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB34959
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 90-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
MMSKLGVLLTICLLLFPHTAVPLDGDQHADQPAERLQDDISSEHHPMLNSIRRREQNQFMSFTSVKLRDSRGERCCGPTACMAGCRPCCG
Physicochemical Analysis
C421H685N131O129S12
WY
L
10030.59
7.04
14
10
29
+0
22.34
-0.311
71.56
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
375
3.74
25
Residue Composition
number
5
A
8
R
2
N
6
D
7
C
4
E
5
Q
6
G
4
H
3
I
10
L
2
K
5
M
3
F
6
P
7
S
4
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 5 R: 8 N: 2 D: 6 C: 7 E: 4 Q: 5 G: 6 H: 4 I: 3 L: 10 K: 2 M: 5 F: 3 P: 6 S: 7 T: 4 W: 0 Y: 0 V: 3
Chemical Descriptors
90
C421H685N131O129S12
10030.59
7.04
+0
22.34
-0.311
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus textile (Cloth-of-gold cone)
Neurotoxin
Conotoxin TxMMSK-06
cone snail
Conotoxin M superfamily
Evidence at transcript level
Amidation Cleavage on pair of basic residues Disulfide bond Hydroxylation Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct.
Additional Detail Fields 7 fields
Amidation Cleavage on pair of basic residues Disulfide bond Hydroxylation Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at transcript level
Conotoxin M superfamily
Conotoxin TxMMSK-06
TISSUE SPECIFICITY: Expressed by the venom duct.
cone snail