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Peptide record

TPDB34782

Neurotoxin Toxicity standard
74 amino acids
Basic Information
3D PDB MODEL
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TPDB34782
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 74-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
MKTGMIICLLLIAFMDADGSPGDTLYSQKTADTDSGMKRFQKTFQKRRCVFCPKEPCCDGDQCMTAPGTGPFCG
Physicochemical Analysis
C344H547N93O106S12
NHW
G
8066.41
7.54
9
8
23
+1
11.82
-0.238
46.22
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
23.12
22
Residue Composition
number
4
A
3
R
0
N
7
D
7
C
1
E
4
Q
8
G
0
H
3
I
4
L
6
K
5
M
5
F
5
P
3
S
7
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 4 R: 3 N: 0 D: 7 C: 7 E: 1 Q: 4 G: 8 H: 0 I: 3 L: 4 K: 6 M: 5 F: 5 P: 5 S: 3 T: 7 W: 0 Y: 1 V: 1
Chemical Descriptors
74
C344H547N93O106S12
8066.41
7.54
+1
11.82
-0.238
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin. {ECO:0000305}.

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus imperialis (Imperial cone)
Neurotoxin
Probable neurotoxin..
Conotoxin Im6.10 (Conopeptide im029)
cone snail
Evidence at protein level
Cleavage on pair of basic residues Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
Additional Detail Fields 6 fields
Cleavage on pair of basic residues Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at protein level
Conotoxin Im6.10 (Conopeptide im029)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
cone snail