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Peptide record

TPDB34742

Neurotoxin Toxicity standard
83 amino acids
Basic Information
3D PDB MODEL
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TPDB34742
Neurotoxin Toxicity
Toxicity and safety peptides
Peptipedia
standard
No
A 83-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
MKVTLIAILTCAAVLVLHTTAAEELEESQLMEVGMPDTELAAVDEERLFECSISCEIEKKGESCKPKKCKGGWKCKFNMCVKV
Physicochemical Analysis
C397H659N101O123S11
Y
E
9167.86
4.96
12
14
33
-3
28.40
0.072
89.28
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
64.08
18
Residue Composition
number
7
A
1
R
1
N
2
D
7
C
12
E
1
Q
4
G
1
H
4
I
8
L
10
K
4
M
2
F
2
P
4
S
5
T
1
W
0
Y
7
V
Amino Acid Distribution
A: 7 R: 1 N: 1 D: 2 C: 7 E: 12 Q: 1 G: 4 H: 1 I: 4 L: 8 K: 10 M: 4 F: 2 P: 2 S: 4 T: 5 W: 1 Y: 0 V: 7
Chemical Descriptors
83
C397H659N101O123S11
9167.86
4.96
-3
28.40
0.072
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Lethal neurotoxin that blocks neuromuscular transmission. {ECO:0000250}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Cyriopagopus schmidti (Chinese bird spider) (Haplopelma schmidti)
Neurotoxin Postsynaptic neurotoxin
Lethal neurotoxin that blocks neuromuscular transmission..
U1-theraphotoxin-Hs1f (U1-TRTX-Hs1f) (Huwentoxin-2a) (Huwentoxin-IIa)
spider
Neurotoxin 12 (Hwtx-2) family, 02 (Hwtx-2) subfamily
Evidence at transcript level
Disulfide bond Neurotoxin Postsynaptic neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom gland.
Additional Detail Fields 7 fields
Disulfide bond Neurotoxin Postsynaptic neurotoxin Secreted Signal Toxin
Neurotoxin Postsynaptic neurotoxin
Evidence at transcript level
Neurotoxin 12 (Hwtx-2) family, 02 (Hwtx-2) subfamily
U1-theraphotoxin-Hs1f (U1-TRTX-Hs1f) (Huwentoxin-2a) (Huwentoxin-IIa)
TISSUE SPECIFICITY: Expressed by the venom gland.
spider