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Peptide record

TPDB34657

Neurotoxin Toxicity standard
77 amino acids
Basic Information
3D PDB MODEL
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TPDB34657
Neurotoxin Toxicity
Toxicity and safety peptides
Peptipedia
standard
No
A 77-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
MKVFSFTIGLVVIISLFAFALAYDEETDLMKKLVEMERAIEQRIICAPEGGPCVVGIGCCKGYSCAPGLLGLVGHCQ
Physicochemical Analysis
C370H595N91O103S9
NW
G
8254.88
4.98
7
8
37
-2
8.68
0.732
110.13
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
40.64
15
Residue Composition
number
6
A
2
R
0
N
2
D
6
C
6
E
2
Q
9
G
1
H
7
I
8
L
4
K
3
M
4
F
3
P
3
S
2
T
0
W
2
Y
7
V
Amino Acid Distribution
A: 6 R: 2 N: 0 D: 2 C: 6 E: 6 Q: 2 G: 9 H: 1 I: 7 L: 8 K: 4 M: 3 F: 4 P: 3 S: 3 T: 2 W: 0 Y: 2 V: 7
Chemical Descriptors
77
C370H595N91O103S9
8254.88
4.98
-2
8.68
0.732
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Intrathorax injection into crickets causes paralysis prolonged for more than 60 minutes, followed by recovery. {ECO:0000269|PubMed:15246762}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Macrothele gigas (Japanese funnel web spider)
Neurotoxin
Intrathorax injection into crickets causes paralysis prolonged for more than 60 minutes, followed by recovery..
U8-hexatoxin-Mg1a (U8-HXTX-Mg1a) (Neurotoxin magi-7)
spider
Neurotoxin 14 (magi-1) family, 05 (ICK-7) subfamily
Evidence at protein level
Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom gland.
Additional Detail Fields 7 fields
Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at protein level
Neurotoxin 14 (magi-1) family, 05 (ICK-7) subfamily
U8-hexatoxin-Mg1a (U8-HXTX-Mg1a) (Neurotoxin magi-7)
TISSUE SPECIFICITY: Expressed by the venom gland.
spider