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Peptide record

TPDB34649

Neurotoxin Toxicity standard
109 amino acids
Basic Information
3D PDB MODEL
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TPDB34649
Neurotoxin Toxicity
Toxicity and safety peptides
Peptipedia
standard
No
A 109-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
MKVLVIIALCLVAFQSALSKKIENFESYIEDLKSEARECIPLYNDCTAFKYNNNCCKDPEKKYQYKCSCIVCKEGKEQCTCQRKETVESMMKCVRFVKKVGEKVIEKVG
Physicochemical Analysis
C550H898N144O163S14
HW
K
12584.89
8.22
20
15
40
+5
35.51
-0.293
77.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
8075
64.16
34
Residue Composition
number
5
A
3
R
5
N
3
D
11
C
12
E
4
Q
3
G
0
H
7
I
6
L
17
K
3
M
4
F
2
P
6
S
3
T
0
W
5
Y
10
V
Amino Acid Distribution
A: 5 R: 3 N: 5 D: 3 C: 11 E: 12 Q: 4 G: 3 H: 0 I: 7 L: 6 K: 17 M: 3 F: 4 P: 2 S: 6 T: 3 W: 0 Y: 5 V: 10
Chemical Descriptors
109
C550H898N144O163S14
12584.89
8.22
+5
35.51
-0.293
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Insect toxin. Causes paralysis in larvae of C.vicina by depolarizing membranes at the neuromuscular junction. {ECO:0000269|PubMed:23088912}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Lachesana tarabaevi (Spider)
Neurotoxin
Insect toxin. Causes paralysis in larvae of C.vicina by depolarizing membranes at the neuromuscular junction..
Latartoxin-2a (LtTx-2a)
spider
Neurotoxin 19 (CSTX) family, 11 (latartoxin) subfamily
Evidence at protein level
Amidation Direct protein sequencing Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:23088912}.
Additional Detail Fields 7 fields
Amidation Direct protein sequencing Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at protein level
Neurotoxin 19 (CSTX) family, 11 (latartoxin) subfamily
Latartoxin-2a (LtTx-2a)
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:23088912}.
spider