TPDB

3D PDB MODEL

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TPDB ID TPDB34643

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 150-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MKVLFFVAAVVAVSLAQDQGPPPLPKFLDGADQATKDAFAALAQTFKDDTDKQVEDAVQQFVNDHPAIKDAYEAEKKEVLAAQQAAEEEHKKLVAALPPDAQKADAESTAIADDASLTLAAKHDKIVQTFESLPPAVKEELNKLNQQGQS

FASTA

>TPDB34643|Toxicity|length=150
MKVLFFVAAVVAVSLAQDQGPPPLPKFLDGADQATKDAFAALAQTFKDDTDKQVEDAVQQFVNDHPAIKDAYEAEKKEVLAAQQAAEEEHKKLVAALPPDAQKADAESTAIADDASLTLAAKHDKIVQTFESLPPAVKEELNKLNQQGQS

Formula C715H1134N188O232S1

Absent Amino Acids RCW

Common Amino Acids A

Mass 16108.05

PI 4.39

Basic Residues 18

Acidic Residues 26

Hydrophobic Residues 66

Net Charge -11

Boman Index 51.97

Hydrophobicity -0.378

Aliphatic Index 84.13

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1490

Absorbance 280nm 9.25

Polar Residues 29

number

29

A

0

R

3

N

15

D

0

C

11

E

14

Q

3

G

3

H

3

I

13

L

15

K

1

M

7

F

9

P

5

S

6

T

0

W

1

Y

12

V

Amino Acid Distribution

A: 29 R: 0 N: 3 D: 15 C: 0 E: 11 Q: 14 G: 3 H: 3 I: 3 L: 13 K: 15 M: 1 F: 7 P: 9 S: 5 T: 6 W: 0 Y: 1 V: 12

Length

150

Formula

C715H1134N188O232S1

Mass

16108.05

PI

4.39

Net Charge

-11

Boman Index

51.97

Hydrophobicity

-0.378

Evidence 1 Activity

Source & Reference

Database Source NA