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Peptide record

TPDB34505

Neurotoxin Toxicity standard
94 amino acids
Basic Information
3D PDB MODEL
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TPDB34505
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 94-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
MKLTCMMIVALLFLTAWTFVTAVDSKNELENRGGWGQAGGWGKLFPMARDEMKNSEVSKLDNKRKCAAAGEACVIPIIGNVFCCKGYCLFVCIS
Physicochemical Analysis
C457H726N120O126S12
H
AG
10302.24
8.18
11
8
43
+3
6.85
0.309
85.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
18365
178.26
22
Residue Composition
number
9
A
3
R
5
N
3
D
7
C
5
E
1
Q
9
G
0
H
5
I
8
L
8
K
5
M
5
F
2
P
4
S
4
T
3
W
1
Y
7
V
Amino Acid Distribution
A: 9 R: 3 N: 5 D: 3 C: 7 E: 5 Q: 1 G: 9 H: 0 I: 5 L: 8 K: 8 M: 5 F: 5 P: 2 S: 4 T: 4 W: 3 Y: 1 V: 7
Chemical Descriptors
94
C457H726N120O126S12
10302.24
8.18
+3
6.85
0.309
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus quercinus (Oak cone)
Neurotoxin
Conotoxin Qc6.1
cone snail
Conotoxin O1 superfamily
Evidence at transcript level
Cleavage on pair of basic residues Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct.
Additional Detail Fields 7 fields
Cleavage on pair of basic residues Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at transcript level
Conotoxin O1 superfamily
Conotoxin Qc6.1
TISSUE SPECIFICITY: Expressed by the venom duct.
cone snail