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Peptide record

TPDB34482

Neurotoxin Toxicity standard
90 amino acids
Basic Information
3D PDB MODEL
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TPDB34482
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 90-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
MKLTILLLVAALLVLTQARTERRRVKSRKTSSTYDDEMATFCWSYWNEFQYSYPYTYVQPCLTLGKACTTNSDCCSKYCNTKMCKINWEG
Physicochemical Analysis
C465H724N122O137S10
H
T
10536.20
8.61
12
7
35
+5
6.55
-0.334
66.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
27305
259.15
39
Residue Composition
number
5
A
5
R
4
N
3
D
7
C
4
E
3
Q
2
G
0
H
2
I
9
L
7
K
3
M
2
F
2
P
7
S
11
T
3
W
7
Y
4
V
Amino Acid Distribution
A: 5 R: 5 N: 4 D: 3 C: 7 E: 4 Q: 3 G: 2 H: 0 I: 2 L: 9 K: 7 M: 3 F: 2 P: 2 S: 7 T: 11 W: 3 Y: 7 V: 4
Chemical Descriptors
90
C465H724N122O137S10
10536.20
8.61
+5
6.55
-0.334
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin. {ECO:0000305}.

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus imperialis (Imperial cone)
Neurotoxin
Probable neurotoxin..
Conotoxin Im6.2 (Conopeptide im018)
cone snail
Conotoxin O2 superfamily
Evidence at protein level
Amidation Cleavage on pair of basic residues Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
Additional Detail Fields 7 fields
Amidation Cleavage on pair of basic residues Disulfide bond Knottin Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at protein level
Conotoxin O2 superfamily
Conotoxin Im6.2 (Conopeptide im018)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
cone snail