TPDB

3D PDB MODEL

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TPDB ID TPDB34331

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 149-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MKLFIILATATLLIAATQAKYLRDEGFDLGETQMSSKCTRQVKMMEPELVKCNRYIAMDIMDDKYEEALSRIQGEGCESEEKFLRGCCVAMKEMEDECVCEWMKMMVENQKGRIGETLMRKGIRDLKELPNKCGISEMECHSRGNWYYV

FASTA

>TPDB34331|Toxicity|length=149
MKLFIILATATLLIAATQAKYLRDEGFDLGETQMSSKCTRQVKMMEPELVKCNRYIAMDIMDDKYEEALSRIQGEGCESEEKFLRGCCVAMKEMEDECVCEWMKMMVENQKGRIGETLMRKGIRDLKELPNKCGISEMECHSRGNWYYV

Formula C740H1200N202O228S22

Absent Amino Acids

Common Amino Acids E

Mass 17280.21

PI 5.04

Basic Residues 23

Acidic Residues 26

Hydrophobic Residues 58

Net Charge -4

Boman Index 47.92

Hydrophobicity -0.403

Aliphatic Index 72.01

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 18950

Absorbance 280nm 109.66

Polar Residues 35

number

8

A

9

R

4

N

7

D

9

C

19

E

5

Q

10

G

1

H

9

I

12

L

13

K

13

M

3

F

2

P

6

S

6

T

2

W

5

Y

6

V

Amino Acid Distribution

A: 8 R: 9 N: 4 D: 7 C: 9 E: 19 Q: 5 G: 10 H: 1 I: 9 L: 12 K: 13 M: 13 F: 3 P: 2 S: 6 T: 6 W: 2 Y: 5 V: 6

Length

149

Formula

C740H1200N202O228S22

Mass

17280.21

PI

5.04

Net Charge

-4

Boman Index

47.92

Hydrophobicity

-0.403

Evidence 1 Activity

Source & Reference

Database Source NA