TPDB

3D PDB MODEL

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TPDB ID TPDB34293

Activity

Neurotoxin Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 115-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MKITAALYVLFFLKIALGDFSEGNENDLVESLPEKLSEADIPVLKKLEAIEDPLLEKVFLQHAEADRNARPKRCAKKRNWCGKNEDCCCPMKCIYAWYNQQGSCQTTITGLFKKC

FASTA

>TPDB34293|Neurotoxin;Toxicity|length=115
MKITAALYVLFFLKIALGDFSEGNENDLVESLPEKLSEADIPVLKKLEAIEDPLLEKVFLQHAEADRNARPKRCAKKRNWCGKNEDCCCPMKCIYAWYNQQGSCQTTITGLFKKC

Formula C581H924N154O169S10

Absent Amino Acids

Common Amino Acids LK

Mass 13091.26

PI 7.49

Basic Residues 18

Acidic Residues 16

Hydrophobic Residues 45

Net Charge +1

Boman Index 27.76

Hydrophobicity -0.310

Aliphatic Index 83.22

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 15970

Absorbance 280nm 121.99

Polar Residues 29

number

10

A

4

R

6

N

6

D

8

C

10

E

4

Q

5

G

1

H

6

I

13

L

13

K

2

M

5

F

5

P

4

S

4

T

2

W

3

Y

4

V

Amino Acid Distribution

A: 10 R: 4 N: 6 D: 6 C: 8 E: 10 Q: 4 G: 5 H: 1 I: 6 L: 13 K: 13 M: 2 F: 5 P: 5 S: 4 T: 4 W: 2 Y: 3 V: 4

Length

115

Formula

C581H924N154O169S10

Mass

13091.26

PI

7.49

Net Charge

+1

Boman Index

27.76

Hydrophobicity

-0.310

Evidence 1 Activity

Source & Reference

Database Source NA