TPDB

3D PDB MODEL

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TPDB ID TPDB34257

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 138-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MKFVIALAALLAVACAAPTPKPARPTPAKGDFRNEFDHLIVAAAVQRFHDLEEFLLKLSEQVADLEKTKNREEKAKILREITIADGLVVGGRTYFEKELKRTDLDLVEKFNFEAVLATIGILDRDLKALATRVNAIKV

FASTA

>TPDB34257|Toxicity|length=138
MKFVIALAALLAVACAAPTPKPARPTPAKGDFRNEFDHLIVAAAVQRFHDLEEFLLKLSEQVADLEKTKNREEKAKILREITIADGLVVGGRTYFEKELKRTDLDLVEKFNFEAVLATIGILDRDLKALATRVNAIKV

Formula C696H1140N188O197S2

Absent Amino Acids W

Common Amino Acids A

Mass 15357.97

PI 8.67

Basic Residues 24

Acidic Residues 21

Hydrophobic Residues 67

Net Charge +1

Boman Index 38.14

Hydrophobicity 0.026

Aliphatic Index 111.09

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1490

Absorbance 280nm 9.70

Polar Residues 17

number

20

A

9

R

4

N

9

D

1

C

12

E

2

Q

5

G

2

H

8

I

18

L

13

K

1

M

8

F

5

P

1

S

8

T

0

W

1

Y

11

V

Amino Acid Distribution

A: 20 R: 9 N: 4 D: 9 C: 1 E: 12 Q: 2 G: 5 H: 2 I: 8 L: 18 K: 13 M: 1 F: 8 P: 5 S: 1 T: 8 W: 0 Y: 1 V: 11

Length

138

Formula

C696H1140N188O197S2

Mass

15357.97

PI

8.67

Net Charge

+1

Boman Index

38.14

Hydrophobicity

0.026

Evidence 1 Activity

Source & Reference

Database Source NA