TPDB

3D PDB MODEL

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TPDB ID TPDB34201

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 140-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVEKGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRTDLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY

FASTA

>TPDB34201|Toxicity|length=140
MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVEKGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRTDLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY

Formula C752H1200N184O216S8

Absent Amino Acids C

Common Amino Acids E

Mass 16531.38

PI 5.24

Basic Residues 25

Acidic Residues 27

Hydrophobic Residues 66

Net Charge -3

Boman Index 45.65

Hydrophobicity -0.329

Aliphatic Index 92.71

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 12950

Absorbance 280nm 78.34

Polar Residues 21

number

11

A

5

R

4

N

7

D

0

C

20

E

3

Q

5

G

1

H

9

I

17

L

19

K

8

M

9

F

1

P

4

S

5

T

1

W

5

Y

6

V

Amino Acid Distribution

A: 11 R: 5 N: 4 D: 7 C: 0 E: 20 Q: 3 G: 5 H: 1 I: 9 L: 17 K: 19 M: 8 F: 9 P: 1 S: 4 T: 5 W: 1 Y: 5 V: 6

Length

140

Formula

C752H1200N184O216S8

Mass

16531.38

PI

5.24

Net Charge

-3

Boman Index

45.65

Hydrophobicity

-0.329

Evidence 1 Activity

Source & Reference

Database Source NA