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Peptide record

TPDB34185

Neurotoxin Toxicity standard
75 amino acids
Basic Information
3D PDB MODEL
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TPDB34185
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 75-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
MKFFTCLLLLLVVLTVVFDNVDACDRSCTGVMGHPSCATCCACFTSAGKRHADGQHSRMKVRTGAKNLLKRMPLH
Physicochemical Analysis
C353H580N106O97S11
EIWY
L
8213.80
8.97
14
4
30
+6
8.80
0.251
81.87
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
375
4.57
20
Residue Composition
number
6
A
5
R
2
N
4
D
7
C
0
E
1
Q
5
G
4
H
0
I
9
L
5
K
4
M
4
F
2
P
4
S
6
T
0
W
0
Y
7
V
Amino Acid Distribution
A: 6 R: 5 N: 2 D: 4 C: 7 E: 0 Q: 1 G: 5 H: 4 I: 0 L: 9 K: 5 M: 4 F: 4 P: 2 S: 4 T: 6 W: 0 Y: 0 V: 7
Chemical Descriptors
75
C353H580N106O97S11
8213.80
8.97
+6
8.80
0.251
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin. {ECO:0000305}.

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus imperialis (Imperial cone)
Neurotoxin
Probable neurotoxin..
Conotoxin Im23.5 (Conopeptide im028)
cone snail
Evidence at protein level
Cleavage on pair of basic residues Disulfide bond Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
Additional Detail Fields 6 fields
Cleavage on pair of basic residues Disulfide bond Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at protein level
Conotoxin Im23.5 (Conopeptide im028)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
cone snail