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Peptide record

TPDB34066

Toxicity standard
60 amino acids
Basic Information
3D PDB MODEL
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TPDB34066
Toxicity
Toxicity and safety peptides
Peptipedia
standard
No
A 60-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
MICYSHKTPQPSATITCEEKTCYKKSVRKLPAIVAGRGCGCPSKEMLVAIHCCRSDKCNE
Physicochemical Analysis
C277H462N82O84S10
FW
C
6605.81
8.51
12
5
17
+5
17.54
-0.325
60.17
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3480
52.68
21
Residue Composition
number
4
A
3
R
1
N
1
D
8
C
4
E
1
Q
3
G
2
H
4
I
2
L
7
K
2
M
0
F
4
P
5
S
4
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 4 R: 3 N: 1 D: 1 C: 8 E: 4 Q: 1 G: 3 H: 2 I: 4 L: 2 K: 7 M: 2 F: 0 P: 4 S: 5 T: 4 W: 0 Y: 2 V: 3
Chemical Descriptors
60
C277H462N82O84S10
6605.81
8.51
+5
17.54
-0.325
Evidence Records 1 records
Evidence 1 Activity

Activity

LC50
Toxicity
1000 µg/mL
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: LC50>1000 µg/mL | Cytotoxicity: HUVEC: LC50>300 µg/mL

Target

erythrocytes

Source & Reference

NA
DRAMP
J Venom Res. 2014 Jun 19 5:16-21.