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Peptide record

TPDB33979

Neurotoxin Toxicity standard
73 amino acids
Basic Information
3D PDB MODEL
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TPDB33979
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 73-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
MGVFRCCLAAALVVVCLSRMGGTEPLESNHEDERRADDTSGDDCVDTNEDCVNWASTGQCEANPSYMRENCRK
Physicochemical Analysis
C324H515N101O118S10
I
DCE
8033.86
4.19
8
14
22
-7
25.27
-0.563
53.42
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7365
91.67
23
Residue Composition
number
6
A
6
R
5
N
7
D
7
C
7
E
1
Q
5
G
1
H
0
I
4
L
1
K
3
M
1
F
2
P
5
S
4
T
1
W
1
Y
6
V
Amino Acid Distribution
A: 6 R: 6 N: 5 D: 7 C: 7 E: 7 Q: 1 G: 5 H: 1 I: 0 L: 4 K: 1 M: 3 F: 1 P: 2 S: 5 T: 4 W: 1 Y: 1 V: 6
Chemical Descriptors
73
C324H515N101O118S10
8033.86
4.19
-7
25.27
-0.563
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin. {ECO:0000305}.

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus imperialis (Imperial cone)
Neurotoxin
Probable neurotoxin..
Conotoxin Im14.3 (Conopeptide im031)
cone snail
Evidence at protein level
Cleavage on pair of basic residues Disulfide bond Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
Additional Detail Fields 6 fields
Cleavage on pair of basic residues Disulfide bond Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at protein level
Conotoxin Im14.3 (Conopeptide im031)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:30893765}.
cone snail