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Peptide record

TPDB33902

Neurotoxin Toxicity standard
117 amino acids
Basic Information
3D PDB MODEL
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TPDB33902
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 117-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
MGFRVLVLVVMATTSALPFTFSEEPGRSPFRPALRSEEAQALRHGLTLLLARRADGQPPDMRQPEMRRPEMRRPEVRQPEFAETPVGQKRGGLGRCIYNCMNSGGGLSFIQCKTMCY
Physicochemical Analysis
C569H920N174O162S11
W
R
13143.29
9.98
18
11
42
+6
27.78
-0.411
65.04
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3230
24.58
26
Residue Composition
number
8
A
15
R
2
N
2
D
4
C
9
E
6
Q
11
G
1
H
2
I
11
L
2
K
7
M
6
F
11
P
6
S
6
T
0
W
2
Y
6
V
Amino Acid Distribution
A: 8 R: 15 N: 2 D: 2 C: 4 E: 9 Q: 6 G: 11 H: 1 I: 2 L: 11 K: 2 M: 7 F: 6 P: 11 S: 6 T: 6 W: 0 Y: 2 V: 6
Chemical Descriptors
117
C569H920N174O162S11
13143.29
9.98
+6
27.78
-0.411
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus villepinii (Villepin's cone)
Neurotoxin
Conotoxin vil14a (Conotoxin vil14.1)
cone snail
Conotoxin R superfamily
Evidence at protein level
3D-structure Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:16331958}.
Additional Detail Fields 7 fields
3D-structure Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at protein level
Conotoxin R superfamily
Conotoxin vil14a (Conotoxin vil14.1)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:16331958}.
cone snail