TPDB

3D PDB MODEL

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TPDB ID TPDB33710

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 147-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MASGVIVATEAKTLYEEVKKDKKYRYIIYHIKDERVIEVETTGPRDATYSDFVARLQDYKNECRYCVFDFPANIPVEGGGEKSNMSVDRLVLMTWCPESAKIKQKMLYSSSYDALKKALVGVYRYVQACDYEEASEEAIAEAFRKGG

FASTA

>TPDB33710|Toxicity|length=147
MASGVIVATEAKTLYEEVKKDKKYRYIIYHIKDERVIEVETTGPRDATYSDFVARLQDYKNECRYCVFDFPANIPVEGGGEKSNMSVDRLVLMTWCPESAKIKQKMLYSSSYDALKKALVGVYRYVQACDYEEASEEAIAEAFRKGG

Formula C747H1166N194O229S8

Absent Amino Acids

Common Amino Acids E

Mass 16785.12

PI 5.41

Basic Residues 23

Acidic Residues 24

Hydrophobic Residues 63

Net Charge -2

Boman Index 42.16

Hydrophobicity -0.443

Aliphatic Index 74.97

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 23630

Absorbance 280nm 140.78

Polar Residues 37

number

14

A

8

R

3

N

9

D

4

C

15

E

3

Q

8

G

1

H

8

I

7

L

14

K

4

M

4

F

4

P

9

S

6

T

1

W

12

Y

13

V

Amino Acid Distribution

A: 14 R: 8 N: 3 D: 9 C: 4 E: 15 Q: 3 G: 8 H: 1 I: 8 L: 7 K: 14 M: 4 F: 4 P: 4 S: 9 T: 6 W: 1 Y: 12 V: 13

Length

147

Formula

C747H1166N194O229S8

Mass

16785.12

PI

5.41

Net Charge

-2

Boman Index

42.16

Hydrophobicity

-0.443

Evidence 1 Activity

Source & Reference

Database Source NA