TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB33652

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 109-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MAFAGVLSDADVAAALEACKDAGTFDYKKFFKSCGLAAKSTDDVKKAFAIIDQDKSGFIEEDELKLFLQNFKAAARPLTDAETEAFLKAGDSDGDGKIGAEEFAALVTA

FASTA

>TPDB33652|Toxicity|length=109
MAFAGVLSDADVAAALEACKDAGTFDYKKFFKSCGLAAKSTDDVKKAFAIIDQDKSGFIEEDELKLFLQNFKAAARPLTDAETEAFLKAGDSDGDGKIGAEEFAALVTA

Formula C514H799N127O166S3

Absent Amino Acids HW

Common Amino Acids A

Mass 11509.93

PI 4.23

Basic Residues 13

Acidic Residues 21

Hydrophobic Residues 51

Net Charge -8

Boman Index 25.61

Hydrophobicity -0.050

Aliphatic Index 77.34

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1615

Absorbance 280nm 14.03

Polar Residues 16

number

22

A

1

R

1

N

13

D

2

C

8

E

2

Q

8

G

0

H

4

I

9

L

12

K

1

M

10

F

1

P

5

S

5

T

0

W

1

Y

4

V

Amino Acid Distribution

A: 22 R: 1 N: 1 D: 13 C: 2 E: 8 Q: 2 G: 8 H: 0 I: 4 L: 9 K: 12 M: 1 F: 10 P: 1 S: 5 T: 5 W: 0 Y: 1 V: 4

Length

109

Formula

C514H799N127O166S3

Mass

11509.93

PI

4.23

Net Charge

-8

Boman Index

25.61

Hydrophobicity

-0.050

Evidence 1 Activity

Source & Reference

Database Source NA