TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB33640

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 121-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MADLRPPEVEKARLHFDIYDFEGQGKVDYHLLGDLLRSLDLRPTQEMVAKNGWEKKKGQKYMTFEEFLPIYSQVKKDKDCGAYEDLVEGLKVYDKAENGTMMEAELAHVLLSLGENWMIRK

FASTA

>TPDB33640|Toxicity|length=121
MADLRPPEVEKARLHFDIYDFEGQGKVDYHLLGDLLRSLDLRPTQEMVAKNGWEKKKGQKYMTFEEFLPIYSQVKKDKDCGAYEDLVEGLKVYDKAENGTMMEAELAHVLLSLGENWMIRK

Formula C631H986N164O187S7

Absent Amino Acids

Common Amino Acids L

Mass 14086.18

PI 5.07

Basic Residues 21

Acidic Residues 23

Hydrophobic Residues 50

Net Charge -5

Boman Index 39.13

Hydrophobicity -0.614

Aliphatic Index 80.58

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 19940

Absorbance 280nm 141.56

Polar Residues 20

number

7

A

5

R

3

N

10

D

1

C

13

E

4

Q

9

G

3

H

3

I

15

L

13

K

6

M

4

F

4

P

3

S

3

T

2

W

6

Y

7

V

Amino Acid Distribution

A: 7 R: 5 N: 3 D: 10 C: 1 E: 13 Q: 4 G: 9 H: 3 I: 3 L: 15 K: 13 M: 6 F: 4 P: 4 S: 3 T: 3 W: 2 Y: 6 V: 7

Length

121

Formula

C631H986N164O187S7

Mass

14086.18

PI

5.07

Net Charge

-5

Boman Index

39.13

Hydrophobicity

-0.614

Evidence 1 Activity

Source & Reference

Database Source NA