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Peptide record

TPDB33239

Neurotoxin Toxicity standard
63 amino acids
Basic Information
3D PDB MODEL
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TPDB33239
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 63-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
LKCHKAQFPNIETQCKWQTLCFQRDVKPHPSSMIVLRGCTSSCGKGAMCCATDLCNGPSTPST
Physicochemical Analysis
C288H465N85O88S10
Y
C
6846.98
8.32
9
3
16
+4
10.32
-0.294
51.11
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
6000
87.63
26
Residue Composition
number
3
A
2
R
2
N
2
D
8
C
1
E
4
Q
4
G
2
H
2
I
4
L
5
K
2
M
2
F
5
P
6
S
6
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 2 N: 2 D: 2 C: 8 E: 1 Q: 4 G: 4 H: 2 I: 2 L: 4 K: 5 M: 2 F: 2 P: 5 S: 6 T: 6 W: 1 Y: 0 V: 2
Chemical Descriptors
63
C288H465N85O88S10
6846.98
8.32
+4
10.32
-0.294
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Blocks both the muscle-twitch response to nerve stimulation and the response to exogenous acetylcholine.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Bungarus fasciatus (Banded krait) (Pseudoboa fasciata)
Neurotoxin Postsynaptic neurotoxin
Blocks both the muscle-twitch response to nerve stimulation and the response to exogenous acetylcholine.
Short neurotoxin 2 (Fasciatoxin) (Toxin V-II-2)
snake
Three-finger toxin family, Short-chain subfamily, Orphan group XVIII sub-subfamily
Evidence at protein level
Direct protein sequencing Disulfide bond Neurotoxin Postsynaptic neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Neurotoxin Postsynaptic neurotoxin Secreted Toxin
Neurotoxin Postsynaptic neurotoxin
Evidence at protein level
Three-finger toxin family, Short-chain subfamily, Orphan group XVIII sub-subfamily
Short neurotoxin 2 (Fasciatoxin) (Toxin V-II-2)
TISSUE SPECIFICITY: Expressed by the venom gland.
snake