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Peptide record

TPDB33186

Alpha-gliadin peptide p31-43 Anticancer Cell-penetrating Peptides Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB33186
Alpha-gliadin peptide p31-43
Anticancer Cell-penetrating Peptides Toxicity
Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
CancerPPD 2.0 CPPsite3.0 Peptipedia
standard
No
A 13-aa standard natural multi-activity (Anticancer, Cell-penetrating Peptides, and Toxicity) peptide sequence curated from CancerPPD 2.0, CPPsite3.0, and Peptipedia, with an available 3D structural model.
Sequence
LGQQQPFPPQQPY
Physicochemical Analysis
C71H102N18O20
ARNDCEHIKMSTWV
Q
1527.70
5.94
0
0
3
-0
2.08
-1.462
30.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
97.53
6
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
5
Q
1
G
0
H
0
I
1
L
0
K
0
M
1
F
4
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 5 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 4 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
13
C71H102N18O20
1527.70
5.94
-0
2.08
-1.462
Free
L
Linear
Free
Anticancer
Synthetic
Evidence Records 4 records
Evidence 1 Activity

Activity

9.4% growth inhibition at 70 µg/mL
Anticancer

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017
US009669068B2

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

36.3% growth inhibition at 70 µg/mL
Anticancer

Target

Lung Cancer
NCI-H1975
Lung

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017
US009669068B2
Evidence 3 Activity

Activity

26.2% growth inhibition at 70 µg/mL
Anticancer

Target

Pancreatic Cancer
PANC-1
Pancreas

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017
US009669068B2
Evidence 4 Activity

Activity

Mean apoptotic rate
Mean apoptotic rate = 36% at 200 µg/mL
Anticancer

Target

Lung Cancer
A-549
Lung

Assay & Model

TUNEL assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017
US009669068B2