TPDB

3D PDB MODEL

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TPDB ID TPDB32431

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 132-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

IRTVFRVTCRARFITELSEFIPGAGVRLQCKDGENGNVTFTEVGYTRAEGLYSMLIERDHKNEFCEITLLSSSRKDCDEIPVEGWVKPSLKFMLNTVNGTTRTINPLGFFKKEALPKCPQVFNKLGMYPPDM

FASTA

>TPDB32431|Toxicity|length=132
IRTVFRVTCRARFITELSEFIPGAGVRLQCKDGENGNVTFTEVGYTRAEGLYSMLIERDHKNEFCEITLLSSSRKDCDEIPVEGWVKPSLKFMLNTVNGTTRTINPLGFFKKEALPKCPQVFNKLGMYPPDM

Formula C668H1056N180O194S9

Absent Amino Acids

Common Amino Acids ELT

Mass 15001.36

PI 8.12

Basic Residues 19

Acidic Residues 16

Hydrophobic Residues 48

Net Charge +2

Boman Index 30.31

Hydrophobicity -0.279

Aliphatic Index 75.98

Half Life

Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 10220

Absorbance 280nm 68.13

Polar Residues 34

number

4

A

9

R

7

N

5

D

5

C

11

E

2

Q

10

G

1

H

7

I

11

L

9

K

4

M

9

F

8

P

6

S

11

T

1

W

3

Y

9

V

Amino Acid Distribution

A: 4 R: 9 N: 7 D: 5 C: 5 E: 11 Q: 2 G: 10 H: 1 I: 7 L: 11 K: 9 M: 4 F: 9 P: 8 S: 6 T: 11 W: 1 Y: 3 V: 9

Length

132

Formula

C668H1056N180O194S9

Mass

15001.36

PI

8.12

Net Charge

+2

Boman Index

30.31

Hydrophobicity

-0.279

Evidence 1 Activity

Source & Reference

Database Source NA