TPDB

3D PDB MODEL

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TPDB ID TPDB32194

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 134-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

HTMEHYLKTYLSWLTEEQKEKLKEMKEAGKTKAEIQHEVMHFYDQLHGEEKQQATEKLKVGCKMLLKGVIGEEKVVELRNMKEAGADIQELQQKVEKMLSEVTDEKQKEKVHEYGPACKKIFGATTLQHHRRRR

FASTA

>TPDB32194|Toxicity|length=134
HTMEHYLKTYLSWLTEEQKEKLKEMKEAGKTKAEIQHEVMHFYDQLHGEEKQQATEKLKVGCKMLLKGVIGEEKVVELRNMKEAGADIQELQQKVEKMLSEVTDEKQKEKVHEYGPACKKIFGATTLQHHRRRR

Formula C692H1126N198O208S8

Absent Amino Acids

Common Amino Acids EK

Mass 15804.24

PI 8.71

Basic Residues 34

Acidic Residues 24

Hydrophobic Residues 44

Net Charge +3

Boman Index 68.44

Hydrophobicity -1.036

Aliphatic Index 69.10

Half Life

Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 11585

Absorbance 280nm 73.30

Polar Residues 27

number

7

A

5

R

1

N

3

D

2

C

21

E

10

Q

8

G

8

H

4

I

12

L

21

K

6

M

2

F

1

P

2

S

8

T

1

W

4

Y

8

V

Amino Acid Distribution

A: 7 R: 5 N: 1 D: 3 C: 2 E: 21 Q: 10 G: 8 H: 8 I: 4 L: 12 K: 21 M: 6 F: 2 P: 1 S: 2 T: 8 W: 1 Y: 4 V: 8

Length

134

Formula

C692H1126N198O208S8

Mass

15804.24

PI

8.71

Net Charge

+3

Boman Index

68.44

Hydrophobicity

-1.036

Evidence 1 Activity

Source & Reference

Database Source NA