TPDB

3D PDB MODEL

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TPDB ID TPDB31750

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 118-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

GLVPRGSEDKWRNAFDHMLMEEFEEKMDQIEHGLLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDLNMFERYNFETAVSTIEILVKDLAELAKKVKAVKSD

FASTA

>TPDB31750|Toxicity|length=118
GLVPRGSEDKWRNAFDHMLMEEFEEKMDQIEHGLLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDLNMFERYNFETAVSTIEILVKDLAELAKKVKAVKSD

Formula C617H996N164O189S6

Absent Amino Acids C

Common Amino Acids E

Mass 13928.04

PI 5.16

Basic Residues 22

Acidic Residues 24

Hydrophobic Residues 48

Net Charge -4

Boman Index 48.14

Hydrophobicity -0.667

Aliphatic Index 85.17

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 9970

Absorbance 280nm 71.58

Polar Residues 22

number

8

A

6

R

4

N

6

D

0

C

18

E

5

Q

4

G

2

H

5

I

15

L

14

K

6

M

5

F

1

P

5

S

5

T

1

W

3

Y

5

V

Amino Acid Distribution

A: 8 R: 6 N: 4 D: 6 C: 0 E: 18 Q: 5 G: 4 H: 2 I: 5 L: 15 K: 14 M: 6 F: 5 P: 1 S: 5 T: 5 W: 1 Y: 3 V: 5

Length

118

Formula

C617H996N164O189S6

Mass

13928.04

PI

5.16

Net Charge

-4

Boman Index

48.14

Hydrophobicity

-0.667

Evidence 1 Activity

Source & Reference

Database Source NA