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Peptide record

TPDB31739

Antifungal Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB31739
Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Antifungipept Peptipedia
standard
No
A 30-aa standard-residue multi-activity (Antifungal and Toxicity) peptide sequence curated from Antifungipept and Peptipedia, with an available 3D structural model.
Sequence
GLPTCGETCFGGTCNTPGCTCDPWPICTRD
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C127H193N35O44S6
AQHKMSYV
CT
3106.50
3.70
1
3
4
-2
1.12
-0.197
26.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
1.89
13
Residue Composition
number
0
A
1
R
1
N
2
D
6
C
1
E
0
Q
5
G
0
H
1
I
1
L
0
K
0
M
1
F
4
P
0
S
6
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 2 C: 6 E: 1 Q: 0 G: 5 H: 0 I: 1 L: 1 K: 0 M: 0 F: 1 P: 4 S: 0 T: 6 W: 1 Y: 0 V: 0
Chemical Descriptors
30 reviewed residue count
C127H193N35O44S6 sequence-only estimate (linear, free termini)
3106.50 sequence-only estimate (linear, free termini)
3.70 sequence-only estimate (linear, free termini)
-2 sequence-only estimate (linear, free termini)
1.12 sequence-only estimate (linear, free termini)
-0.197 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:11535828] It has hemolytic activity

Target

erythrocytes

Source & Reference

NA
DRAMP
Proc Natl Acad Sci U S A. 2001 Sep 11 98(19):10614-9.