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Peptide record

TPDB31734

Poca A Anticancer Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB31734
Poca A
Anticancer Toxicity
Cancer-related peptides Toxicity and safety peptides
CancerPPD 2.0 Peptipedia
standard
No
A 30-aa standard natural multi-activity (Anticancer and Toxicity) peptide sequence curated from CancerPPD 2.0 and Peptipedia, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
GLPCAESCVFIPCTITAILGCSCRDRVCYD
Physicochemical Analysis
C135H218N36O42S6
NQHKMW
C
3209.79
4.31
2
3
11
-1
1.80
0.770
91.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
58.10
11
Residue Composition
number
2
A
2
R
0
N
2
D
6
C
1
E
0
Q
2
G
0
H
3
I
2
L
0
K
0
M
1
F
2
P
2
S
2
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 2 C: 6 E: 1 Q: 0 G: 2 H: 0 I: 3 L: 2 K: 0 M: 0 F: 1 P: 2 S: 2 T: 2 W: 0 Y: 1 V: 2
Chemical Descriptors
30
C135H218N36O42S6
3209.79
4.31
-1
1.80
0.770
Cyclized
L
Cyclic
Cyclized
Antimicrobial,Cytotoxic
Pombalia calceolaria
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 1.8 µM
Anticancer
1.8 µM

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2018

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.