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Peptide record

TPDB31718

Neurotoxin Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB31718
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
GLIDVRCYDSSQCE
Physicochemical Analysis
C64H102N18O25S2
ANHKMFPTW
DCS
1587.74
3.70
1
3
4
-2
3.92
-0.307
76.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1615
101.72
6
Residue Composition
number
0
A
1
R
0
N
2
D
2
C
1
E
1
Q
1
G
0
H
1
I
1
L
0
K
0
M
0
F
0
P
2
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 2 C: 2 E: 1 Q: 1 G: 1 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
14
C64H102N18O25S2
1587.74
3.70
-2
3.92
-0.307
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Blocker of potassium channels (Kv).

Target

voltage-gated potassium channel (Kv)

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Leiurus quinquestriatus quinquestriatus (Egyptian scorpion) (Deathstalker scorpion)
Neurotoxin Ion channel impairing toxin Potassium channel impairing toxin
Blocker of potassium channels (Kv).
Leiurutoxin-3 (Leiurutoxin III) (Potassium channel toxin alpha-KTx)
scorpion
Short scorpion toxin superfamily, Potassium channel inhibitor family
Evidence at protein level
Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Potassium channel impairing toxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:1280139}.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Potassium channel impairing toxin Secreted Toxin
Neurotoxin Ion channel impairing toxin Potassium channel impairing toxin
Evidence at protein level
Short scorpion toxin superfamily, Potassium channel inhibitor family
Leiurutoxin-3 (Leiurutoxin III) (Potassium channel toxin alpha-KTx)
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:1280139}.
scorpion