TPDB

3D PDB MODEL

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TPDB ID TPDB31411

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 136-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

GDYPFEPRRQIEHCRQRCQDRSQGFRETRECLETCEKRAGFDDEPSKEVDSYTTDTRSRDPQQEFRQCRHRCQTQEEGGRQQRKCEQRCEKQLERQQGYDDEEFGQGRSNIGAPVRNYDDCTEMCGGSPLCALFCE

FASTA

>TPDB31411|Toxicity|length=136
GDYPFEPRRQIEHCRQRCQDRSQGFRETRECLETCEKRAGFDDEPSKEVDSYTTDTRSRDPQQEFRQCRHRCQTQEEGGRQQRKCEQRCEKQLERQQGYDDEEFGQGRSNIGAPVRNYDDCTEMCGGSPLCALFCE

Formula C656H1025N219O230S13

Absent Amino Acids W

Common Amino Acids R

Mass 16076.46

PI 4.91

Basic Residues 25

Acidic Residues 29

Hydrophobic Residues 22

Net Charge -6

Boman Index 68.97

Hydrophobicity -1.575

Aliphatic Index 23.68

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 6710

Absorbance 280nm 41.74

Polar Residues 47

number

3

A

19

R

2

N

11

D

12

C

18

E

16

Q

11

G

2

H

2

I

4

L

4

K

1

M

6

F

6

P

6

S

7

T

0

W

4

Y

2

V

Amino Acid Distribution

A: 3 R: 19 N: 2 D: 11 C: 12 E: 18 Q: 16 G: 11 H: 2 I: 2 L: 4 K: 4 M: 1 F: 6 P: 6 S: 6 T: 7 W: 0 Y: 4 V: 2

Length

136

Formula

C656H1025N219O230S13

Mass

16076.46

PI

4.91

Net Charge

-6

Boman Index

68.97

Hydrophobicity

-1.575

Evidence 1 Activity

Source & Reference

Database Source NA