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Peptide record

TPDB30912

Neurotoxin Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB30912
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
GCCGSFACRFGCVPCCV
Physicochemical Analysis
C69H106N20O19S6
NDEQHILKMTWY
C
1712.08
7.63
1
0
5
+1
-2.31
1.335
40.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
375
21.90
7
Residue Composition
number
1
A
1
R
0
N
0
D
6
C
0
E
0
Q
3
G
0
H
0
I
0
L
0
K
0
M
2
F
1
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 6 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
17
C69H106N20O19S6
1712.08
7.63
+1
-2.31
1.335
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Intracranial injection into mice causes circular motion, barrel rolling and convulsions. {ECO:0000269|PubMed:15924437, ECO:0000269|PubMed:17042781}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus marmoreus (Marble cone)
Neurotoxin
Intracranial injection into mice causes circular motion, barrel rolling and convulsions..
Conotoxin mr3a
cone snail
Conotoxin M superfamily
Evidence at protein level
Direct protein sequencing Disulfide bond Hydroxylation Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:14717596}.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Hydroxylation Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Conotoxin M superfamily
Conotoxin mr3a
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:14717596}.
cone snail